Impact of Alternative Nicotine-Delivery Products on Combustible Cigarette Use

PHASE2CompletedINTERVENTIONAL
Enrollment

209

Participants

Timeline

Start Date

September 9, 2020

Primary Completion Date

May 23, 2022

Study Completion Date

May 23, 2022

Conditions
Nicotine Dependence
Interventions
DEVICE

Juul Electronic cigarette

The juul e-cigarette pods contain 0.7 ml nicotine by volume / 5% nicotine by weight.

OTHER

Very Low Nicotine Cigarettes

These very low nicotine cigarettes (VLNCs) consist of reduced nicotine cigarettes containing 0.03 mg of nicotine; these VLNCs were obtained from National Institute on Drug Abuse (NIDA's) Drug Supply Program (NOT-DA-14-004).

DRUG

Active Nicotine Patch

Active nicotine patches, with dosing based on the package insert (\>10 cigs/day = 21 mg patch and \<11 cigs/day = 14 mg patches).

OTHER

Placebo Patch

Placebo patch containing no nicotine.

Trial Locations (2)

53233

UW Center for Tobacco Research and Intervention, Milwaukee

53711

University of Wisconsin Center for Tobacco Research and Intervention, Madison

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

University of Wisconsin, Madison

OTHER

NCT04084210 - Impact of Alternative Nicotine-Delivery Products on Combustible Cigarette Use | Biotech Hunter | Biotech Hunter