Brain-injured Patients Extubation Readiness Study

NARecruitingINTERVENTIONAL
Enrollment

660

Participants

Timeline

Start Date

February 9, 2020

Primary Completion Date

February 13, 2027

Study Completion Date

October 13, 2027

Conditions
Mechanical Ventilator WeaningAcute Brain InjuryAltered Level of ConsciousnessMechanical VentilationAirway Control
Interventions
PROCEDURE

Extubation readiness clinical score

"After treatment of the acute neurological condition, eligibility for a spontaneous breathing trial will be assessed once a day.~In the intervention group, after a successful spontaneous breathing trial in unconscious patients, the score will be evaluated.~If the score is \> 9, extubation has to be completed."

PROCEDURE

Usual Care

"After treatment of the acute neurological condition, eligibility for a spontaneous breathing trial will be assessed once a day.~In the control group, after a successful spontaneous breathing trial in unconscious patients, the extubation will be achieved according to usual care."

Trial Locations (21)

Unknown

RECRUITING

CHU, Angers

RECRUITING

CHU, Bordeaux

RECRUITING

CHU, Bordeaux

TERMINATED

CH, Bourg-en-Bresse

RECRUITING

CHU, Caen

RECRUITING

CHU, Clermont-Ferrand

COMPLETED

CHU, Grenoble

RECRUITING

CHU, La Réunion

RECRUITING

CHU, Lille

RECRUITING

Hospices Civils de Lyon, Lyon

WITHDRAWN

APHM, Marseille

RECRUITING

CHU, Montpellier

COMPLETED

CHU, Nantes

TERMINATED

Pasteur 2 Hospital - University Hospital, Nice

RECRUITING

CHU, Nîmes

RECRUITING

Fondation Ophtalmologique Adolphe de Rothschild, Paris

RECRUITING

CHU, Poitiers

RECRUITING

CHU, Rennes

COMPLETED

CHU, Saint-Etienne

RECRUITING

CHU, Toulouse

TERMINATED

CH, Valence

All Listed Sponsors
collaborator

ANARLF Network

UNKNOWN

collaborator

Direction Générale de l'Offre de Soin (DGOS)

UNKNOWN

lead

University Hospital, Clermont-Ferrand

OTHER