Efficacy and Safety of Combination Therapy of Moderate-intensity Statin and Ezetimibe Compared to High-intensity Statin

PHASE4CompletedINTERVENTIONAL
Enrollment

270

Participants

Timeline

Start Date

March 15, 2018

Primary Completion Date

June 15, 2019

Study Completion Date

September 17, 2019

Conditions
Cardiovascular Diseases
Interventions
DRUG

Efficacy and safety of combination therapy of moderate-intensity statin and ezetimibe compared to high-intensity statin

"This study is a multicenter, randomized, open-label, parallel, phase IV trial. The study is planned to include 272 patients with clinical ASCVD requiring optimal statin therapy.~After enrollment, subjects are randomized into two groups in a 1:1 manner. patients in combination therapy group(rosuvastation 10mg and ezetimibe 10mg daily) will be provided a fixed-dose single pill comibation and patients in the intensive statin group will receive rosuvastatin 20mg daily."

Trial Locations (2)

13620

Seoul National University Bundang Hospital, Seongnam-si

06511

Seoul National University Bundang Hospital, Seongnam-si

All Listed Sponsors
collaborator

Yuhan Corporation

INDUSTRY

lead

Seoul National University Bundang Hospital

OTHER

NCT04080310 - Efficacy and Safety of Combination Therapy of Moderate-intensity Statin and Ezetimibe Compared to High-intensity Statin | Biotech Hunter | Biotech Hunter