Neuromodulation of Spinal Locomotor Circuitry to Elicit Stepping After Pediatric Spinal Cord Injury

NAEnrolling by invitationINTERVENTIONAL
Enrollment

8

Participants

Timeline

Start Date

April 12, 2021

Primary Completion Date

January 31, 2026

Study Completion Date

January 31, 2026

Conditions
Spinal Cord Injuries
Interventions
DEVICE

Biostim-5 transcutaneous spinal stimulator

"Transcutaneous spinal stimulation (TcStim): The 5-channel stimulator capable of generating (41) pain-free biphasic rectangular waveform of 0.3- to 1.0-ms pulses with a frequency of 5-10 kHz will be used to stimulate at single or multi-site spinal levels.~TcStim will be delivered in combination with activity based locomotor training in 5 - 10 minute of stimulation at sub-motor threshold daily (5x/week) for 60 sessions"

OTHER

Transcutaneous Spinal Stimulator + Activity Based Locomotor Training

Participants will receive a combination of Activity-based locomotor training (AB-LT)+TcStim daily (5x/week) for 60 sessions and will consist of a minimum of 55-60 min on the TM for facilitated standing/stepping followed by 30 min of activities off TM in sitting, standing, or stepping.

Trial Locations (1)

40202

Department of Neurosurgery, University of Louisville, Louisville

All Listed Sponsors
collaborator

Kentucky Spinal Cord and Head Injury Research Trust and Board

UNKNOWN

collaborator

Kosair Charities, Inc.

OTHER

lead

University of Louisville

OTHER