DIFFIR - Geriatric Distal Femur Fixation Versus Replacement

NARecruitingINTERVENTIONAL
Enrollment

140

Participants

Timeline

Start Date

October 1, 2021

Primary Completion Date

December 10, 2025

Study Completion Date

October 10, 2028

Conditions
Distal Femur Fracture
Interventions
PROCEDURE

Distal femoral replacement

The distal portion of the femur (up to two thirds) is excised and replaced by a endoprosthesis incorporating a hinged total knee replacement.

PROCEDURE

Surgical Fixation (ORIF)

A trained orthopaedic surgeon uses open or minimally invasive reduction techniques and achieves stable fixation with internal fixation devices (plates/screws or intramedullary nail) to restore structural integrity and alignment of the distal femur

Trial Locations (1)

Unknown

RECRUITING

St Michael's Hospital - Unity Health Toronto, Toronto

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Mount Sinai Hospital, Canada

OTHER

collaborator

NYU Langone Health

OTHER

collaborator

Brigham and Women's Hospital

OTHER

collaborator

Queen Elizabeth II Health Sciences Centre

OTHER

collaborator

Hamilton Health Sciences Corporation

OTHER

collaborator

Yale New Haven Health System Center for Healthcare Solutions

OTHER

collaborator

Oregon Health and Science University

OTHER

collaborator

OrthoCincy Orthopaedics & Sports Medicine

UNKNOWN

collaborator

University of California

OTHER

collaborator

Hospital for Special Surgery, New York

OTHER

collaborator

Stanford University

OTHER

collaborator

Cedars-Sinai Medical Center

OTHER

collaborator

Thunder Bay Regional Health Sciences Centre

OTHER

collaborator

University of California, San Francisco

OTHER

collaborator

University of Arkansas

OTHER

collaborator

University of Calgary

OTHER

collaborator

Ascension Health

INDUSTRY

collaborator

University of Otago

OTHER

collaborator

Gold Coast University Hospital, Australia

UNKNOWN

collaborator

Humber River Hospital

OTHER

lead

Unity Health Toronto

OTHER