Defining a Dosing Regimen With Maximal Absorption for Oral Iron Supplementation During Pregnancy

NACompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

October 24, 2019

Primary Completion Date

June 30, 2022

Study Completion Date

June 30, 2022

Conditions
Iron Deficiency Anemia of Pregnancy
Interventions
DIETARY_SUPPLEMENT

Labeled iron solution (60mg and 120mg Ferrous Fumarate)

3 doses of 60mg iron as ferrous fumarate are given on one consecutive day and one alternate day (e.g., days 1, 2, 4); 3 doses of 120mg iron as ferrous fumarate are given on one consecutive and one alternate day (e.g., days 20, 21, 23); 3 doses of 120mg iron as ferrous fumarate are given on one consecutive and one 3rd day (e.g., days 37, 38, 41). Iron doses are labeled with 4mg of a stable isotope in 200ml deionized water (57Fe, 58Fe or 54Fe). Participants will be randomly assigned to start with 60mg iron daily vs alternate day dosing, 120mg daily vs alternate day dosing or 120mg daily vs every-third day dosing.

Trial Locations (1)

73170

Mahidol University, Salaya

All Listed Sponsors
collaborator

Mahidol University

OTHER

lead

Swiss Federal Institute of Technology

OTHER

NCT04074707 - Defining a Dosing Regimen With Maximal Absorption for Oral Iron Supplementation During Pregnancy | Biotech Hunter | Biotech Hunter