Reducing Anticholinergic Bladder Medication Use in Spinal Cord Injury With Home Neuromodulation

NACompletedINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

November 19, 2019

Primary Completion Date

April 20, 2023

Study Completion Date

April 20, 2023

Conditions
Chronic Spinal Cord InjuryNeurogenic Bladder
Interventions
DEVICE

High Dose

Electrodes 2 inch by 2 inch will be placed according to anatomic landmarks,with the negative electrode behind the internal malleolus and the positive electrode 10cm superior to the negative electrode, verified with rhythmic flexion of the toes secondary to stimulation of the flexor digitorum and hallicus brevis. The intensity level will be set to the amperage immediately under the threshold for motor contraction. If the patient perceives pain, the intensity will be lowered until comfortable. Stimulation frequency of 10 Hz and pulse width of 200ms in continuous mode will be used.

DEVICE

Low dose

Toe flexion will be attempted, as in the TTNS protocol. Then the stimulation will be reduced to 1 mA for 30 minutes

Trial Locations (1)

77030

The University of Texas Health Science Center at Houston, Houston

All Listed Sponsors
collaborator

National Center for Advancing Translational Sciences (NCATS)

NIH

lead

The University of Texas Health Science Center, Houston

OTHER

NCT04074616 - Reducing Anticholinergic Bladder Medication Use in Spinal Cord Injury With Home Neuromodulation | Biotech Hunter | Biotech Hunter