NCT04073797View on ClinicalTrials.gov

PET Imaging of Inflammation and Lipid Lowering Study

NARecruitingINTERVENTIONAL
Enrollment

63

Participants

Timeline

Start Date

March 20, 2023

Primary Completion Date

October 1, 2025

Study Completion Date

March 1, 2026

Conditions
HypercholesterolemiaHypercholesterolemia, FamilialAtherosclerosisCarotid Artery Plaque
Interventions
DRUG

Inclisiran

Inclisiran 284 mg, one injection

DIAGNOSTIC_TEST

68Ga-DOTATATE PET-MRI

68Ga-DOTATATE PET-MRI at baseline and 12 weeks

DRUG

Colchicine

Colchicine 500 mcg tablet once daily

Trial Locations (1)

Unknown

RECRUITING

University of Cambridge, Cambridge

Sponsors

Collaborators (1)

GE Healthcare
All Listed Sponsors
collaborator

Cambridge University Hospitals NHS Foundation Trust

OTHER

collaborator

Wellcome Trust

OTHER

collaborator

GE Healthcare

INDUSTRY

collaborator

Lund University

OTHER

lead

University of Cambridge

OTHER