Sentinel Node Biopsy in Endometrial Cancer

PHASE3RecruitingINTERVENTIONAL
Enrollment

760

Participants

Timeline

Start Date

January 18, 2021

Primary Completion Date

January 31, 2031

Study Completion Date

February 28, 2031

Conditions
Endometrial Cancer Stage ISentinel Lymph NodeSurgery
Interventions
PROCEDURE

TH BSO with SNB Note: If participants (≤45yo), Grade 1 endometrial adenocarcinoma with myometrial invasion <50%, wish to retain their ovaries a BSO may be omitted

"Removal of uterus, tubes and ovaries with a sentinel node biopsy. A tracer dye (ICG) +/- Methylene Blue Dye is injected into the surroundings of the primary tumour, it is transported via local lymphatic channels towards the draining lymphatic basin, and the first node that the tracer reaches is called the sentinel node. These one or two nodes are thought to be first involved with cancer spread."

PROCEDURE

TH BSO without retroperitoneal node dissection Note: If participants (≤45yo), Grade 1 endometrial adenocarcinoma with myometrial invasion <50%, wish to retain their ovaries a BSO may be omitted

Removal of uterus, tubes and ovaries without retroperitoneal node dissection

Trial Locations (20)

2050

RECRUITING

Chris O'Brien Lifehouse, Camperdown

2170

RECRUITING

Liverpool Hospital, Liverpool

3052

RECRUITING

Royal Women's Hospital, Parkville

3084

RECRUITING

Mercy Hospital for Women, Heidelberg

4000

RECRUITING

St Andrews War Memorial Hospital, Spring Hill

4029

RECRUITING

Royal Brisbane and Women's Hospital, Herston

4053

RECRUITING

North West Private Hospital, Everton Park

4066

RECRUITING

The Wesley Hospital, Auchenflower

4101

RECRUITING

Mater Hospital, South Brisbane

4215

NOT_YET_RECRUITING

Gold Coast University Hospital, Southport

4556

RECRUITING

Buderim Private Hospital, Buderim

33100

RECRUITING

Azienda Sanitaria Universitaria Friuli Centrale (ASUFC), Udine

77030

RECRUITING

Houston Methodist Hospital, Houston

119074

RECRUITING

National University Hospital and National University Cancer Institute, Singapore

Unknown

NOT_YET_RECRUITING

Hospital Britanico, Ciudad

NOT_YET_RECRUITING

Hospital Municipal Vila Santa Catarina, Santa Catarina

RECRUITING

Fundacao Antonio Prudente, AC Camargo Cancer Center, São Paulo

NOT_YET_RECRUITING

Hospital Israelita Albert Einstein, São Paulo

NOT_YET_RECRUITING

Instituto Nacional de Cancerología, Astorga

15090-000

NOT_YET_RECRUITING

Hospital de Base, São José do Rio Preto

All Listed Sponsors
collaborator

The University of Queensland

OTHER

lead

Queensland Centre for Gynaecological Cancer

OTHER_GOV

NCT04073706 - Sentinel Node Biopsy in Endometrial Cancer | Biotech Hunter | Biotech Hunter