Chemotherapy and Pelvic Hypofractionated Radiation Followed by Brachytherapy for Cervical Cancer

NARecruitingINTERVENTIONAL
Enrollment

82

Participants

Timeline

Start Date

July 1, 2019

Primary Completion Date

July 30, 2024

Study Completion Date

December 30, 2024

Conditions
Cervical Cancer
Interventions
RADIATION

Hypofractionated therapy

All patients will be treated with an external beam of 37.5 Gray in 15 fractions (2.5 Gray / fraction). They will be treated once a day, 5 days a week. If photon energy 6 MV or 10 MV is used, the patient should be treated with a 4-field technique using the anterior/posterior field and 2 lateral fields. The specification of the dose is in terms of a dose to a point at or near the center of the target volume. For all field dispositions, the dose specification point is the common isocenter of all beams.

RADIATION

Standard therapy

All patients will be treated with external beam radiotherapy with 50 Gray in 25 fractions (1.8-2 Gray / fraction). They will be treated once a day, 5 days a week. If photon energy 6 MV or 10 MV is used, the patient should be treated with a 4-field technique using anterior/posterior fields and 2 lateral fields. The specification of the dose is in terms of a dose to a point at or near the center of the target volume. For all field dispositions, the dose specification point is the common isocenter of all beams.

Trial Locations (1)

14080

RECRUITING

David Cantu de Leon, Mexico City

All Listed Sponsors
lead

National Institute of Cancerología

OTHER_GOV