103
Participants
Start Date
April 7, 2020
Primary Completion Date
December 31, 2025
Study Completion Date
December 31, 2025
Avelumab
Given IV
Biopsy Procedure
Undergo biopsy of tumor
Biospecimen Collection
Correlative studies
Computed Tomography
Undergo CT scan
Hypofractionated Radiation Therapy
Undergo hypofractionated RT
Peposertib
Given PO
RECRUITING
Bellevue Hospital Center, New York
RECRUITING
Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York
RECRUITING
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York
RECRUITING
NYP/Weill Cornell Medical Center, New York
RECRUITING
University of Pittsburgh Cancer Institute (UPCI), Pittsburgh
RECRUITING
MedStar Georgetown University Hospital, Washington D.C.
RECRUITING
Sibley Memorial Hospital, Washington D.C.
RECRUITING
VCU Massey Comprehensive Cancer Center, Richmond
RECRUITING
Emory University Hospital Midtown, Atlanta
RECRUITING
Emory University Hospital/Winship Cancer Institute, Atlanta
RECRUITING
Emory Saint Joseph's Hospital, Atlanta
RECRUITING
University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami
RECRUITING
UM Sylvester Comprehensive Cancer Center at Coral Gables, Coral Gables
RECRUITING
UM Sylvester Comprehensive Cancer Center at Kendall, Miami
RECRUITING
UM Sylvester Comprehensive Cancer Center at Aventura, Aventura
RECRUITING
UM Sylvester Comprehensive Cancer Center at Plantation, Plantation
RECRUITING
UM Sylvester Comprehensive Cancer Center at Deerfield Beach, Deerfield Beach
RECRUITING
Vanderbilt University/Ingram Cancer Center, Nashville
ACTIVE_NOT_RECRUITING
Wayne State University/Karmanos Cancer Institute, Detroit
ACTIVE_NOT_RECRUITING
Weisberg Cancer Treatment Center, Farmington Hills
RECRUITING
University of Wisconsin Carbone Cancer Center - Eastpark Medical Center, Madison
RECRUITING
University of Wisconsin Carbone Cancer Center - University Hospital, Madison
RECRUITING
Northwestern University, Chicago
RECRUITING
UCHealth University of Colorado Hospital, Aurora
RECRUITING
Huntsman Cancer Institute/University of Utah, Salt Lake City
RECRUITING
City of Hope Comprehensive Cancer Center, Duarte
RECRUITING
UC San Diego Moores Cancer Center, La Jolla
RECRUITING
UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care, Irvine
RECRUITING
UC Irvine Health/Chao Family Comprehensive Cancer Center, Orange
SUSPENDED
University of California Davis Comprehensive Cancer Center, Sacramento
RECRUITING
Smilow Cancer Hospital-Derby Care Center, Derby
RECRUITING
Smilow Cancer Hospital Care Center-Fairfield, Fairfield
RECRUITING
Smilow Cancer Hospital Care Center at Glastonbury, Glastonbury
RECRUITING
Smilow Cancer Hospital Care Center at Greenwich, Greenwich
RECRUITING
Smilow Cancer Hospital Care Center - Guilford, Guilford
RECRUITING
Smilow Cancer Hospital Care Center at Saint Francis, Hartford
RECRUITING
Smilow Cancer Center/Yale-New Haven Hospital, New Haven
RECRUITING
Yale University, New Haven
RECRUITING
Yale-New Haven Hospital North Haven Medical Center, North Haven
RECRUITING
Smilow Cancer Hospital Care Center at Long Ridge, Stamford
RECRUITING
Smilow Cancer Hospital-Torrington Care Center, Torrington
RECRUITING
Smilow Cancer Hospital Care Center-Trumbull, Trumbull
RECRUITING
Smilow Cancer Hospital-Waterbury Care Center, Waterbury
RECRUITING
Smilow Cancer Hospital Care Center - Waterford, Waterford
RECRUITING
Rutgers Cancer Institute of New Jersey, New Brunswick
RECRUITING
Smilow Cancer Hospital Care Center - Westerly, Westerly
National Cancer Institute (NCI)
NIH