Pediatric Acute Respiratory Distress Syndrome Asia Study

CompletedOBSERVATIONAL
Enrollment

738

Participants

Timeline

Start Date

August 1, 2019

Primary Completion Date

March 31, 2023

Study Completion Date

July 7, 2024

Conditions
Acute Respiratory Distress SyndromePediatric Intensive Care UnitMechanical Ventilation
Interventions
OTHER

Ventilation protocol

An evidence based ventilation protocol will be implemented at participating sites. This will include limits on peak inspiratory pressure (28cmH2O), driving pressure (16cmH2O), tidal volume (mild 8ml/kg, mod/severe 6ml/kg), positive end expiratory pressure to fraction of inspired oxygen table, permissive hypercarbia (mild allow pH 7.30, mod/severe allow pH 7.20) and permissive hypoxia (mild SpO2 92-97%, mod/severe SpO2 88-92%).

Trial Locations (19)

229899

KK Women's and Children's Hospital, Singapore

Unknown

Guangzhou Women and Children's Medical Center, Guangzhou

Shengjing hospital of China Medical University, Shenyang

Children's Hospital of Fudan University, Shanghai

Chongqing Hospital, Chongqing

Hong Kong Children's Hospital, Kowloon Bay

Post Graduate Institute of Medical Education and Research, Chandigarh

Sanglah Hospital Denpasar, Denpasar

Harapan Kita Children and Women hospital, Jakarta

Hyogo Prefectural Kobe Children's Hospital, Hyōgo

Universiti Kebangsaan Malaysia Medical Centre, Bandar Tun Razak

Sarawak General Hospital, Kuching

University Malaya Medical Centre, Kuala Lumpur

Aga Khan University Hospital, Karachi

National University Hospital, Singapore, Singapore

Siriraj Hospital, Bangkok Noi

King Chulalongkorn Memorial Hospital, Bangkok

Ramathibodi hospital, Bangkok

National Hospital of Pediatrics, Đống Đa

All Listed Sponsors
collaborator

Children's Hospital of Chongqing Medical University

OTHER

collaborator

Guangzhou Women and Children's Medical Center

OTHER

collaborator

Shengjing Hospital

OTHER

collaborator

Children's Hospital of Fudan University

OTHER

collaborator

Hong Kong Children's Hospital

OTHER

collaborator

Sarawak General Hospital

OTHER

collaborator

Universiti Kebangsaan Malaysia Medical Centre

OTHER

collaborator

University of Malaya

OTHER

collaborator

King Chulalongkorn Memorial Hospital

OTHER

collaborator

Siriraj Hospital

OTHER

collaborator

Ramathibodi Hospital

OTHER

collaborator

National Children's Hospital, Vietnam

OTHER

collaborator

Post Graduate Institute of Medical Education and Research, Chandigarh

OTHER

collaborator

Rumah Sakit Anak dan Bunda Harapan Kita

UNKNOWN

collaborator

Sanglah General Hospital

OTHER

collaborator

General Hospital of North Sumatera University

UNKNOWN

collaborator

Hyogo Prefectural Kobe Children's Hospital

OTHER

collaborator

Aga Khan University

OTHER

collaborator

National University Hospital, Singapore

OTHER

collaborator

Singapore Clinical Research Institute

OTHER

lead

KK Women's and Children's Hospital

OTHER_GOV

NCT04068038 - Pediatric Acute Respiratory Distress Syndrome Asia Study | Biotech Hunter | Biotech Hunter