TAS1R1, TAS1R3, TLR2, TLR4, CA6 Gene Polymorphism on Dental Caries

CompletedOBSERVATIONAL
Enrollment

200

Participants

Timeline

Start Date

January 15, 2018

Primary Completion Date

October 15, 2019

Study Completion Date

November 20, 2019

Conditions
High Caries RiskLow Caries Risk
Interventions
GENETIC

high caries risk

DNAs were obtained from epithelial cells in buccal mucosa and were extracted with Genomic DNA Isolation Kit Genotyping for a variant was carried out on a Roche Applied Science LightCycler® 480 (Roche Diagnostics GmbH, Mannheim, Germany) with real-time polymerase reaction of Taqman

OTHER

caries activity

"Dental caries lesions of all patient scored as initial, moderate or advanced caries~Initial lesion; clinically detectable lesion Moderate; visible signs of enamel breakdown Advanced; enamel was fully cavitaed"

Trial Locations (1)

53000

Recep Tayyip Erdogan University, Rize

All Listed Sponsors
lead

Recep Tayyip Erdogan University Training and Research Hospital

OTHER

NCT04066101 - TAS1R1, TAS1R3, TLR2, TLR4, CA6 Gene Polymorphism on Dental Caries | Biotech Hunter | Biotech Hunter