TEsting for Arterial Disease in Diabetes (TrEAD) Study

CompletedOBSERVATIONAL
Enrollment

305

Participants

Timeline

Start Date

March 4, 2019

Primary Completion Date

October 18, 2019

Study Completion Date

October 18, 2019

Conditions
Diabetic FootPeripheral Arterial DiseaseDiabetic Foot UlcerPeripheral Vascular DiseasesPeripheral Artery DiseaseCritical Limb IschemiaCritical Lower Limb Ischemia
Interventions
DIAGNOSTIC_TEST

Transcutaneous pressure of oxygen (TcPO2)

Measurements will be taken from the dorsum of the foot using an automated machine equipped with Clark electrodes.

DIAGNOSTIC_TEST

Toe Brachial Pressure Index (TBPI)

TBPI will be measured using the photoplethysmography (PPG) method, employing an infrared sensor placed on the hallux and index finger.

DIAGNOSTIC_TEST

Podiatry Ankle Duplex scan (PAD-scan)

Podiatry ankle duplex scan (PAD-scan) involves using an ultrasound machine to visualise the anterior and posterior tibial arteries at the ankle.

DIAGNOSTIC_TEST

Duplex Assist

Continuous Doppler device which gives visual display of arterial spectral waveform at the ankle.

DIAGNOSTIC_TEST

Ankle Brachial Pressure Index (ABPI)

A sphygmomanometer-cuff placed at the ankle and a handheld continuous wave Doppler device will be used to measure the systolic pressure of the DPA and PTA.

Trial Locations (2)

TW76AF

West Middlesex University Hospital, London

W21NY

Imperial College NHS Healthcare Trust, London

All Listed Sponsors
lead

Imperial College Healthcare NHS Trust

OTHER

NCT04058626 - TEsting for Arterial Disease in Diabetes (TrEAD) Study | Biotech Hunter | Biotech Hunter