NCT04058470View on ClinicalTrials.gov

Toripalimab Plus Rituximab Followed by R-CHOP for Elderly Patients With Untreated Diffused B Cell Lymphoma

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

140

Participants

Timeline

Start Date

April 24, 2020

Primary Completion Date

December 30, 2023

Study Completion Date

December 30, 2025

Conditions
Diffuse Large B Cell LymphomaHigh-grade B-cell LymphomaFollicular Lymphoma Grade IIIbTransformed LymphomaEBV-Positive DLBCL, NosALK-Positive Anaplastic Large Cell Lymphoma
Interventions
DRUG

Toripalimab, Rituximab

Toripalimab in combination with Rituximab will be administered every 3 weeks up to 4 cycles.

DRUG

R-CHOP Protocol

After toripalimab plus rituximab treatment, R-CHOP regimen will be administered every 3 weeks in combination with R-CHOP up to 6 cycles.

Trial Locations (1)

510515

RECRUITING

Department of hematology department, Nanfang hospital, Guangzhou

All Listed Sponsors
lead

Huiqiang Huang

OTHER