103
Participants
Start Date
September 9, 2019
Primary Completion Date
February 11, 2021
Study Completion Date
February 11, 2021
Fosaprepitant Dimeglumine
Participants received IV fosaprepitant dimeglumine ≤115 mg on Day 1 and ≤80 mg on Days 2 and 3 (dose adjusted for age).
5-HT3 antagonist
All participants received an oral 5-hydroxytryptamine (serotonin; \[5-HT\]) 3 receptor antagonist on Day 1 and had the option to take on Days 2-3. The dose was as per product label or standard of care.
Dexamethasone
Participants received optional oral dexamethasone at the investigator's discretion according to product label or standard of care.
Heim Pal Orszagos Gyermekgyogyaszati Intezet ( Site 0202), Budapest
Borsod-Abauj-Zemplen Megyei Korhaz es Egyetemi OktatoKorhaz ( Site 0203), Miskolc
Szegedi Tudomanyegyetem - Szent-Gyorgyi Albert Klinikai Kozpont ( Site 0201), Szeged
Instituto Nacional de Enfermedades Neoplasicas ( Site 1502), Lima
Clinica Anglo Americana ( Site 1501), Lima
Clinica Delgado ( Site 1503), Lima
St. Jude Children's Research Hospital ( Site 1111), Memphis
LSMUL Kauno Klinikos ( Site 0402), Kaunas
Children's Hospitals and Clinics of Minnesota ( Site 1109), Minneapolis
Ann & Robert H. Lurie Children's Hospital of Chicago ( Site 1106), Chicago
Phoenix Childrens Hospital ( Site 1101), Phoenix
Southern California Permanente Medical Group ( Site 1104), Los Angeles
Blokhin National Medical Oncology ( Site 0701), Moscow
Dmitry Rogachev National Research Center ( Site 0704), Moscow
Clinical Research Center of specialized types medical care-Oncology ( Site 0706), Saint Petersburg
Chelyabinsk Regional Children Clinical Hospital ( Site 0705), Chelyabinsk
Athens Childrens Hospital Aglaia Kyriakou ( Site 0101), Athens
University of Athens - Aghia Sophia Childrens Hospital ( Site 0102), Athens
"University General Hospital of Thessaloniki AHEPA ( Site 0103)", Thessaloniki
Vaiku ligonine VsI VUL Santaros kliniku filialas ( Site 0401), Vilnius
Prinses Maxima Centrum ( Site 0501), Utrecht
Instytut Matki i Dziecka ( Site 0601), Warsaw
Instytut Pomnik Centrum Zdrowia Dziecka ( Site 0602), Warsaw
Leeds Teaching Hospitals NHS Trust ( Site 1002), Leeds
Alder Hey Childrens NHS Foundation Trust Hospital ( Site 1003), Liverpool
Royal Manchester Children's Hospital ( Site 1005), Manchester
Merck Sharp & Dohme LLC
INDUSTRY