Preventive Versus Curative Treatment of Fluid Overload

NARecruitingINTERVENTIONAL
Enrollment

410

Participants

Timeline

Start Date

February 1, 2020

Primary Completion Date

March 1, 2024

Study Completion Date

March 1, 2024

Conditions
Respiratory Insufficiency
Interventions
OTHER

Preventive initiation of fluid removal

"Preventive initiation of fluid removal will be started right after the randomization with intravenous diuretics according to a predefined algorithm based on the urine output every three hours.~The weaning process and post extubation preventive strategy will be protocolized based on the last international guidelines"

OTHER

Curative initiation of fluid removal

"The initiation of fluid removal will be considered by the attending physician only in case of failure to the spontaneous breathing trial with a clinical suspicion of weaning induced pulmonary edema.~The weaning process and post extubation preventive strategy will be protocolized based on the last international guidelines"

Trial Locations (1)

75013

RECRUITING

GH Pitié Salpêtrière - Charles Foix, Paris

All Listed Sponsors
lead

Assistance Publique - Hôpitaux de Paris

OTHER