270
Participants
Start Date
November 12, 2019
Primary Completion Date
May 31, 2023
Study Completion Date
July 12, 2023
Tacrolimus
"The patients will be divided into two groups randomly. Tacrolimus dose: 0.05-0.10 mg/kg/day, BID. The concentration for tacrolimus is 5-10 ng/ml，then reduce the dosage of drugs to maintian the concentration for tacrolimus is \< 5ng/ml. Total duration : 1 year.~Steroid dose: 1.0-1.5 mg/kg, qod or 0.5-0.75 mg/kg/day, qd， then gradually taper the steroid to 5mg/day."
Mycophenolate Mofetil
"The patients will be divided into two groups randomly. Mycophenolate Mofetil dose: 20\~30mg/kg/day，BID. The concentration for MPA-AUC is 30\~50 μg.h/ml，then reduce the dosage of drugs to maintian the concentration for MPA-AUC is ≤40 μg.h/ml. Total duration : 1 year.~Steroid dose: 1.0-1.5 mg/kg, qod or 0.5-0.75 mg/kg/day, qd， then gradually taper the steroid to 5mg/day."
Peking University First Hospital, Beijing
Children's Hospital of Fudan University, Shanghai
Nanjing Children's Hospital, Nanjing
Children's Hospital of Soochow University, Suzhou
Shandong Provincial Hospital, Jinan
The Children Hospital of Zhejiang University School of Medicine, Hangzhou
Children's Hospital of Chongqing Medical University, Chongqing
Second Xiangya Hospital of Central South University, Changsha
Tongji Hospital, Wuhan
Henan Children's Hospital, Zhengzhou
First Affiliated Hospital of Zhongshan Medical University, Guangzhou
Chengdu Women and Children's Center Hospital, Chengdu
Children's Hospital of Fudan University
OTHER
Peking University First Hospital
OTHER
First Affiliated Hospital of Zhongshan Medical University
OTHER
Nanjing Children's Hospital
OTHER
Chengdu Women and Children's Center Hospital
OTHER
Tongji Hospital
OTHER
Second Xiangya Hospital of Central South University
OTHER
Children's Hospital of Chongqing Medical University
OTHER
Children's Hospital of Soochow University
OTHER
Henan Provincial People's Hospital
OTHER
Shandong Provincial Hospital
OTHER_GOV
The Children's Hospital of Zhejiang University School of Medicine
OTHER