Influence of High Vitamin C Dose on Lactate During and After Extracorporeal Circulation

NACompletedINTERVENTIONAL
Enrollment

70

Participants

Timeline

Start Date

March 1, 2023

Primary Completion Date

December 1, 2023

Study Completion Date

September 1, 2024

Conditions
HyperlactatemiaCardiac DiseaseBypass ComplicationValve Disease, HeartVitamin C
Interventions
DIETARY_SUPPLEMENT

ascorbic acid,

The vitamin C group will get high dose of intravenous vitamin C (ascorbic acid) before starting cardiopulmonary bypass, before removing aortic clamp and every 8 hours thereafter for additionaly 24 hours

OTHER

Placebo (saline)

The placebo group will get saline before starting cardiopulmonary bypass, before removing aortic clamp and every 8 hours thereafter for additionaly 24 hours

Trial Locations (1)

2000

Department od anesthesiology, intensive care and pain management, Maribor

All Listed Sponsors
lead

University Medical Centre Maribor

OTHER