Radiotherapy Versus Low-Dose Tamoxifen Following Breast Conserving Surgery for Low-Risk Breast Ductal Carcinoma in Situ

PHASE3RecruitingINTERVENTIONAL
Enrollment

810

Participants

Timeline

Start Date

April 30, 2019

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
Breast Ductal Carcinoma in Situ
Interventions
DRUG

Low-dose tamoxifen

Low-dose tamoxifen is not inferior than radiotherapy in decreasing ipsilateral breast tumor recurrence and side effect

RADIATION

Whole breast radiotherapy

Ipsilateral breast tumor recurrence and side effect

Trial Locations (1)

100

RECRUITING

National Taiwan University Hospital, Taipei

All Listed Sponsors
collaborator

Tri-Service General Hospital

OTHER

collaborator

Koo Foundation Sun Yat-Sen Cancer Center

OTHER

collaborator

Kaohsiung Medical University

OTHER

collaborator

Kyoto University

OTHER

collaborator

Mackay Memorial Hospital

OTHER

lead

National Taiwan University Hospital

OTHER