Theta-burst Stimulation on Cognitive Function in the Patients with Young-onset Alzheimer's Disease Dementia

NAEnrolling by invitationINTERVENTIONAL
Enrollment

70

Participants

Timeline

Start Date

January 3, 2020

Primary Completion Date

June 30, 2026

Study Completion Date

June 30, 2026

Conditions
Alzheimer Disease, Early Onset
Interventions
DEVICE

Theta-burst stimulation (TBS)

We will perform standard intermittent TBS (iTBS) parameters to left DLPFC of every patient in the study. The frequency parameters of TBS are 3-pulse 50-Hz bursts, every 200 ms at 5 Hz, and the intensity is 90% of active motor threshold. A single session of iTBS contains 2 s of TBS repeated every 10 s for 20 times. In this study, we will give two sessions of iTBS separated by 15 min.

Trial Locations (1)

333

Chang Gung Memorial Hospital, Taoyuan District

All Listed Sponsors
lead

Chang Gung Memorial Hospital

OTHER