23
Participants
Start Date
December 31, 2019
Primary Completion Date
May 25, 2022
Study Completion Date
September 1, 2022
Experimental Intraosseous vancomycin 500mg in 250 mL NS
500mg of Vancomycin in 250 mL of normal saline will be injected into a pre-specified region of the greater trochanter during primary total hip arthroplasty.
Standard IV administration of vancomycin
IV antibiotics (cefepime \& vancomycin) are started in pre-op approximately 1 hour prior to incision (vancomycin dose weight-based at approximately 15mg/kg, generally 1000-1750mg in 500 mL NS).
Houston Methodist Hospital, Houston
The Methodist Hospital Research Institute
OTHER