8
Participants
Start Date
October 9, 2019
Primary Completion Date
August 1, 2021
Study Completion Date
August 1, 2021
Ketamine
Subjects in the intervention arm will receive infusion dosing as noted in arm/group descriptions at the time of cord clamping. Duration of infusion will be 12 hours. Concentrations of ketamine and ketamine metabolites (nor-ketamine, NKET; and dehydro-nor-ketamine, DHNK) are measured in maternal plasma and urine as well as breastmilk. Maternal side effects, adverse events, and efficacy endpoints will be measured over the 12 hour infusion and over 15 hours after infusion discontinuation.
UPMC Montefiore Hospital CTRC, Pittsburgh
Minhnoi C Wroble Biglan, Pittsburgh
University of Pittsburgh
OTHER
Grace Lim, MD, MS
OTHER