Relation betwEen Abdominal Aorta and Carotid Artery Responses to SymPathetic stimulatiON uSing duplEx Ultrasound

CompletedOBSERVATIONAL
Enrollment

60

Participants

Timeline

Start Date

October 1, 2019

Primary Completion Date

August 1, 2020

Study Completion Date

October 5, 2020

Conditions
Abdominal Aortic Aneurysm
Interventions
DIAGNOSTIC_TEST

Carotid artery reactivity test (CAR-test)

The CAR test will be applied to stimulate the sympathetic nervous system. This thermal stimulus is known to elevate blood pressure via sympathetic pathways, so it can be used to study the vascular response to sympathetic activation. The participant will submerge their left hand in a bucket of ice water (approximately 4 degrees celcius) for 3 minutes, which is reported to be sufficient to induce a maximal dilation in the common carotid artery. At baseline and every minute after the hand is submerged in ice water, the blood pressure will be measured to check whether a sympathetic stimulation is achieved. During this test as well the carotid artery as the abdominal aorta will be visualized using ultrasound.

Trial Locations (2)

Unknown

Rijnstate Hospital, Arnhem

6525GA

Radboudumc, Nijmegen

All Listed Sponsors
collaborator

Radboud University Medical Center

OTHER

lead

Rijnstate Hospital

OTHER

NCT04035252 - Relation betwEen Abdominal Aorta and Carotid Artery Responses to SymPathetic stimulatiON uSing duplEx Ultrasound | Biotech Hunter | Biotech Hunter