NCT04033627View on ClinicalTrials.gov

TCDαβ/CD45RA Haploidentical Transplantation in Children With Leukemia

NAUnknownINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

November 10, 2020

Primary Completion Date

July 18, 2022

Study Completion Date

May 8, 2024

Conditions
Relapsed Pediatric ALLAcute Graft-Versus-Host Disease (Gvhd) Grade IV (Diagnosis)Relapsed Pediatric AML
Interventions
PROCEDURE

In Vitro T cells depletion using CliniMCAS system

Use the CliniMACS TCRα/β and CD45 Systems to deplete TCRα/β+ and CD45RA+ cells from the mobilized peripheral blood stem cells of a haploidentical donor in patients with leukemia.

Trial Locations (1)

Unknown

RECRUITING

Shanghai Children's Medical Center, Shanghai

Sponsors

Collaborators (1)

Miltenyi Biomedicine GmbH
All Listed Sponsors
collaborator

Nanfang Hospital, Southern Medical University

OTHER

collaborator

Children's Hospital of Soochow University

OTHER

collaborator

Chinese University of Hong Kong

OTHER

collaborator

Miltenyi Biomedicine GmbH

INDUSTRY

lead

Shanghai Children's Medical Center

OTHER