Expanded Study of the HighLife 28mm Trans-septal Trans-catheter Mitral Valve in Patients With Moderate-severe or Severe Mitral Regurgitation and at High Surgical Risk

NARecruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

May 28, 2019

Primary Completion Date

December 15, 2026

Study Completion Date

December 15, 2031

Conditions
Mitral Regurgitation
Interventions
DEVICE

HighLife Transcatheter Mitral Valve Replacement

Transcatheter Mitral Valve Replacement

Trial Locations (50)

2010

RECRUITING

St. Vincent's Hospital - Sydney, Darlinghurst

2020

RECRUITING

ZNA Middelheim, Antwerp

2109

WITHDRAWN

Macquarie University Hospital, Sydney

2305

RECRUITING

John Hunter Hospital, Newcastle

3000

RECRUITING

UZ Leuven, Leuven

3004

RECRUITING

The Alfred Hospital, Melbourne

3084

TERMINATED

Warringal Hospital, Heidelberg

4066

RECRUITING

The Wesley Hospital, Auchenflower

5000

RECRUITING

St. Andrew's Hospital, Adelaide

5015

TERMINATED

European Hospital George Pompidou, Paris

6150

RECRUITING

Mount Hospital, Perth

8000

RECRUITING

AZ Sint-Jan, Bruges

20246

RECRUITING

Universitatsklink Hamburg-Eppendorf, Hamburg

31076

RECRUITING

Clinque Pasteur, Toulouse

31400

RECRUITING

Rangueil University Hospital, Toulouse

33600

RECRUITING

CHU Bordeaux, Pessac

35000

RECRUITING

CHU de Rennes, Rennes

53127

RECRUITING

Universitaetsklinikum Bonn, Bonn

79189

TERMINATED

University Heart Center Freiburg - Bad Krozingen, Bad Krozingen

89081

RECRUITING

University Hospital Ulm, Ulm

Unknown

RECRUITING

Princess Alexandra Hospital, Brisbane

RECRUITING

John Hunter Hospital, Newcastle

RECRUITING

North Shore Private Hospital, Sydney

RECRUITING

CHU Lille, Lille

RECRUITING

Medipole Lyon-Villeurbanne, Lyon

RECRUITING

Hopital Prive - Jacques Cartier, Massy

RECRUITING

Centre Hospitalo-Universitaire de Nantes, Nantes

RECRUITING

Centr Cardiologiqque du Nord, Saint-Denis

RECRUITING

CHRU Strasbourg, Strasbourg

RECRUITING

Rangueil University Hospital, Toulouse

RECRUITING

Heart Center, University Hospital Dresden, Dresden

RECRUITING

Mediinisches Versorgungszentrum, Hamburg

TERMINATED

University Hospital Heidelberg, Heidelberg

RECRUITING

Deutsches Herzzentrum Munchen, Munich

TERMINATED

University Medicine Dept of Cardiology, Rostock

RECRUITING

Medical University of Gdansk, Gdansk

RECRUITING

National Heart Center Singapore, Singapore

RECRUITING

Royal Victoria Hospital, Belfast

RECRUITING

Royal Infirmary of Edinburgh, Edinburgh

TERMINATED

Leeds Teaching Hospitals NHS Trust, Leeds

TERMINATED

University Hospitals of Leicester NHS Trust, Leicester

TERMINATED

Barts Heart Center, London

TERMINATED

John Radcliffe, Oxford

04289

RECRUITING

Herzentrum Leipzig, Leipzig

40-635

RECRUITING

Medical University of Silesia Hospital, Katowice

61-848

TERMINATED

University Hospital of Lord's Transfiguration, Poznan

02-097

RECRUITING

Medical University of Warsaw, Warsaw

04-628

RECRUITING

Institute of Cardiology, Warsaw

BN2 5BE

RECRUITING

Brighton and Sussex University Hospital, Brighton

SE1 9RS

RECRUITING

Guy's and St. Thomas' NHS Foundation Trust - St. Thomas Hospital, London

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

ICON plc

INDUSTRY

lead

HighLife SAS

INDUSTRY