Inhaled Steroids for Acute Pharyngitis.

PHASE2/PHASE3CompletedINTERVENTIONAL
Enrollment

200

Participants

Timeline

Start Date

June 1, 2019

Primary Completion Date

May 30, 2022

Study Completion Date

May 30, 2022

Conditions
Acute Pharyngitis
Interventions
DRUG

Budesonide 0.25 MG/ML Inhalant Solution

"Both medications used for the intervention groups are Glucocorticoids. The effect of glucocorticoids in AP can be attributed to their anti-inflammatory actions. They inhabit the formation of the pro-inflammatory mediators in the endothelial cells of the airways. This will decreases the inflammatory reaction at the pharynges which result in a reduction of throat pain.~Studies have shown that the use of a single dose of systemic glucocorticoids for acute pharyngitis did not result in significant adverse events and no serious adverse events were reported (7) (8)."

DRUG

Dexamethasone

"Both medications used for the intervention groups are Glucocorticoids. The effect of glucocorticoids in AP can be attributed to their anti-inflammatory actions. They inhabit the formation of the pro-inflammatory mediators in the endothelial cells of the airways. This will decreases the inflammatory reaction at the pharynges which result in a reduction of throat pain.~Studies have shown that the use of a single dose of systemic glucocorticoids for acute pharyngitis did not result in significant adverse events and no serious adverse events were reported (7) (8)."

DRUG

Normal saline

Placebo for the control group.

Trial Locations (3)

113

Armed Forces Hospital, Muscat

Mortaafah Armed Medical Hospital (MAM), Muscat

Royal Oman Police Hospital, Muscat

All Listed Sponsors
lead

Oman Medical Speciality Board

OTHER_GOV

NCT04027322 - Inhaled Steroids for Acute Pharyngitis. | Biotech Hunter | Biotech Hunter