280
Participants
Start Date
July 12, 2019
Primary Completion Date
March 31, 2025
Study Completion Date
March 31, 2025
Stepped care for nonadherence and depression
"* Problem Solving for Depression and Adherence: A 6-session adherence and depression intervention based on a culturally adapted LifeSteps and Problem Solving Therapy for Depression.~* Stepped Care Assessment for Antidepressant Treatment: If a participant's depression score remains above threshold in Session 6, the study interventionist will refer the participant to a Research Mental Health Nurse for a psychopharmacological assessment to prescribe an antidepressant to augment Problem Solving for Depression and Adherence."
Enhanced Usual Care
Enhanced Usual Care: A combination of 1) clinic-provided adherence counseling, 2) access to providers trained in the World Health Organization Mental Health Gap Intervention Guide (mhGAP), 3) a letter to the participant's medical provider detailing the depression diagnosis, 4) access to the treatment components of the TENDAI intervention at no cost, after the participant has completed their 12-month follow-up assessment.
Marondera Provincial Hospital, Marondera
Massachusetts General Hospital
OTHER
University of Zimbabwe College of Health Sciences
UNKNOWN
National Institute of Mental Health (NIMH)
NIH
King's College London
OTHER