Motor Plasticity, Intermittent Hypoxia and Sleep Apnea

NACompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

July 16, 2021

Primary Completion Date

July 1, 2025

Study Completion Date

July 1, 2025

Conditions
Sleep Apnea, ObstructiveSpinal Cord InjuriesHypoxia
Interventions
PROCEDURE

Induced Acute Intermittent Hypoxia (AIH)

AIH will be administered on days 1-3. Each day entails 15 and 90 second hypoxic intervals (Fraction of Inspired Oxygen (FIO2) = 0.09) alternating with 60-second normoxic intervals (FIO2 = 0.21).

DEVICE

AIH mask

Induced Intermitted hypoxia will be delivered via the AIH mask. The mask has two one-way valves restricting inspiration to the top valve and expiration to the bottom valve. Hypoxic and normoxic gas mixtures will be delivered through the top valve.

Trial Locations (1)

33136

University of Miami, Miami

All Listed Sponsors
collaborator

The Craig H. Neilsen Foundation

OTHER

lead

University of Miami

OTHER

NCT04017767 - Motor Plasticity, Intermittent Hypoxia and Sleep Apnea | Biotech Hunter | Biotech Hunter