A Study Investigating the Efficacy of GON Blocks.

PHASE4CompletedINTERVENTIONAL
Enrollment

8

Participants

Timeline

Start Date

February 14, 2018

Primary Completion Date

December 31, 2019

Study Completion Date

January 23, 2020

Conditions
MigraineChronic Migraine, Headache
Interventions
DRUG

Combined Depo-Medrone and Lidocaine

"Patients will be randomised 1:1 to receive the active or placebo arm. The nerve is located along the superior nuchal line, where it bilaterally lies medial to the occipital artery. The scalp is prepped with alcohol and using 23G needle, the IMPs are injected at a 90 degrees angle till the bony endpoint is obtained. A combination of 2 mls of 2% lidocaine and 80mg methylprednisolone will be administered.~Patients who no longer receive any benefit will be crossed over to the placebo arm."

DRUG

Sodium Chloride 0.9% Inj

Patients will be randomised 1:1 to receive the active or placebo arm. The nerve is located along the superior nuchal line, where it bilaterally lies medial to the occipital artery. The scalp is prepped with alcohol and using 23G needle the 4mls of normal saline (0.9%) are injected at a 90 degrees angle till the bony endpoint is obtained. Patients who no longer receive any benefit will be crossed over to the active arm.

Trial Locations (1)

EC1A 4NP

Barts Health NHS Trust, London

All Listed Sponsors
lead

Barts & The London NHS Trust

OTHER

NCT04017741 - A Study Investigating the Efficacy of GON Blocks. | Biotech Hunter | Biotech Hunter