NCT04012411View on ClinicalTrials.gov

Study of BDNF Pathway Biomarkers in the Cerebrospinal Fluid in Patients With Huntington's Disease

NARecruitingINTERVENTIONAL
Enrollment

135

Participants

Timeline

Start Date

March 3, 2020

Primary Completion Date

February 28, 2026

Study Completion Date

February 28, 2026

Conditions
Huntington Disease
Interventions
PROCEDURE

Brain MRI

Multimodal brain MRI: volumetry, diffusion tensor, functional rest MRI

PROCEDURE

Lumbar Punction

Analysis of BDNF, Tau, NFL and TrkB in cerebrospinal fluid

GENETIC

Blood sample

Analysis of BDNF, Tau, NFL, and Val66Met polymorphism

OTHER

Cognitive evaluation

Symbol Digit Modality Test (SDMT), Stroop test, Trail Making Test, Empan

Trial Locations (1)

Unknown

RECRUITING

University Hospital of Montpellier, Montpellier

All Listed Sponsors
lead

University Hospital, Montpellier

OTHER