NCT04009876View on ClinicalTrials.gov

A Study to Evaluate a Chemotherapy Treatment Followed by Chemo and Radiotherapy in Patients With Rectal Cancer

PHASE2CompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

May 1, 2019

Primary Completion Date

October 21, 2022

Study Completion Date

October 21, 2022

Conditions
Locally Advanced Rectal Cancer (LARC)
Interventions
DRUG

nal-IRI

Treatment with 5-FU/LV + Oxaliplatin + nal-IRI for 8 cycles followed by standard chemoradiation (5 weeks)

PROCEDURE

Surgical resection

Surgical resection of the tumour

OTHER

Watch-and-wait

No surgery approach

DRUG

5-FU/LV

Treatment with 5-FU/LV + Oxaliplatin + nal-IRI for 8 cycles followed by standard chemoradiation (5 weeks)

DRUG

Oxaliplatin

Treatment with 5-FU/LV + Oxaliplatin + nal-IRI for 8 cycles followed by standard chemoradiation (5 weeks)

Trial Locations (4)

28007

Hospital General Universitario Gregorio Marañón, Madrid

28022

Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda

28041

Hospital Universitario 12 de Octubre, Madrid

28050

Hospital Universitario Madrid Sanchinarro, PAU de Sanchinarro

All Listed Sponsors
collaborator

Syntax for Science, S.L

INDUSTRY

lead

Fundación de investigación HM

OTHER

NCT04009876 - A Study to Evaluate a Chemotherapy Treatment Followed by Chemo and Radiotherapy in Patients With Rectal Cancer | Biotech Hunter | Biotech Hunter