Salivary Gland Autotransplantation for Treatment of XRT Induced Xerostomia

NACompletedINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

October 18, 2019

Primary Completion Date

March 10, 2021

Study Completion Date

March 10, 2021

Conditions
XerostomiaHead and Neck Cancer
Interventions
PROCEDURE

Bone Marrow Aspiration

collection of approximately 40 mL of bone marrow aspirate

DIAGNOSTIC_TEST

Ultrasound Imaging of Salivary Glands

Salivary gland size will be measured by ultrasound.

OTHER

Salivary Assay

Whole saliva production rates (sialometry) will be measured under unstimulated (first passive drool method) and stimulated (chewing gum) saliva collection conditions

OTHER

Quality of Life Instruments

Participants will self-assess with the following Quality of Life (QoL) surveys: University of Michigan Xerostomia related quality of life scale (XeQOL), the MD Anderson Dysphagia Index (MDADI), and the VAS xerostomia questionnaire.

Trial Locations (1)

53705

University of Wisconsin Carbone Cancer Center, Madison

All Listed Sponsors
lead

University of Wisconsin, Madison

OTHER

NCT04007081 - Salivary Gland Autotransplantation for Treatment of XRT Induced Xerostomia | Biotech Hunter | Biotech Hunter