NCT04003350View on ClinicalTrials.gov

The Effect of Prolonged Multimodal Analgesic Regimen on Post Hospital Discharge Opioid Use and Pain Control After Primary Total Knee Arthroplasty

NACompletedINTERVENTIONAL
Enrollment

216

Participants

Timeline

Start Date

December 21, 2017

Primary Completion Date

November 26, 2018

Study Completion Date

March 15, 2019

Conditions
Osteo Arthritis Knee
Interventions
DRUG

Oxycodone

Patients are given, for up to 4 weeks, Oxycodone 5m PRN every four hours (up to 30 tablets)

DRUG

Tramadol

Patients are given, for up to 4 weeks, Tramadol 50mg PRN every 6 hours (up to 30 tablets)

DRUG

Tylenol

Tylenol 1000 mg: take as needed every 8 hours

DRUG

Meloxicam

Meloxicam 15 mg as need once per day

DRUG

Gabapentin

•Gabapentin 200 mg with morning and evening Tylenol dose

DRUG

Metaxalone

Metaxalone 800mg TID

DRUG

Esomeprazole 20mg

Esomeprazole 20mg daily

Trial Locations (1)

19148

Rothman Institute, Philadelphia

All Listed Sponsors
lead

Rothman Institute Orthopaedics

OTHER

NCT04003350 - The Effect of Prolonged Multimodal Analgesic Regimen on Post Hospital Discharge Opioid Use and Pain Control After Primary Total Knee Arthroplasty | Biotech Hunter | Biotech Hunter