YIV-906 (Formerly PHY906/KD018) With Sorafenib in HBV(+) Hepatocellular Carcinoma (HCC)

PHASE2CompletedINTERVENTIONAL
Enrollment

62

Participants

Timeline

Start Date

January 10, 2020

Primary Completion Date

March 22, 2024

Study Completion Date

November 19, 2024

Conditions
Advanced Hepatocellular Carcinoma
Interventions
DRUG

Sorafenib+YIV-906

Patients will be given sorafenib (400 mg BID) daily for a 28-day course with YIV-906 (3 capsules, BID) 4 days on and 3 days off weekly in each course.

DRUG

Sorafenib+placebo

Patients will be given sorafenib (400 mg BID) daily for a 28-day course with placebo (3 capsules, BID) 4 days on and 3 days off weekly in each course.

Trial Locations (24)

10065

Memorial Sloan Kettering Cancer Center, New York

11042

Northwell Monter Cancer Institute, Lake Success

11355

Calvin Pan. MD Gastroenterology & Hepatology Clinic, Flushing

44106

University Hospitals Cleveland Medical Center, Cleveland

Unknown

Beijing You'An Hospital, Capital Medical University, Beijing

Cancer Hospital Chinese Academy of Medical Sciences, Beijing

China-Japan Friendship Hospital, Beijing

Foshan Hospital of Traditional Chinese Medicine, Foshan

Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou

The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou

Shenzhen People's Hospital, Shenzhen

The First Affiliated Hospital of Guangxi Medical University, Nanning

Hunan Cancer Hospital, Changsha

LongHua Hospital Shanghai University of Traditional Chinese Medicine, Shanghai

Shanghai Eastern Hepatobiliary Hospital, Shanghai

Shanghai University of Traditional Chinese Medicine Shuguang Hospital, Shanghai

Queen Mary Hospital, Hong Kong

China Medical University Hospital, Taichung

National Cheng Kung University Hospital, Tainan City

Cancer Research Center, Taipei Municipal Wanfang Hospital, Taipei

Taipei Medical University -Shuang Ho Hospital, Ministry of Health and Welfare, Taipei

Taipei Medical University Cancer Center, Taipei

Taipei Veterans General Hospital, Taipei

Chang Gung Memorial Hospital, Linkou, Taoyuan District

All Listed Sponsors
lead

Yiviva Inc.

INDUSTRY

NCT04000737 - YIV-906 (Formerly PHY906/KD018) With Sorafenib in HBV(+) Hepatocellular Carcinoma (HCC) | Biotech Hunter | Biotech Hunter