NCT03997643View on ClinicalTrials.gov

Preservation of Swallowing in Respected Oral Cavity Squamous Cell Carcinoma: Examining Radiation Volume Effects (PRESERVE): A Randomized Trial

PHASE2RecruitingINTERVENTIONAL
Enrollment

90

Participants

Timeline

Start Date

September 6, 2019

Primary Completion Date

September 30, 2026

Study Completion Date

September 30, 2026

Conditions
Head and Neck Cancer
Interventions
RADIATION

Radiotherapy to all dissected areas

Post operative radiation therapy +/- chemotherapy based on historic treatment volumes (including the primary site, dissected areas +/- elective areas

RADIATION

Omit radiation to pN0 neck

post operation radiation therapy +/- chemotherapy that avoids targeting the dissected pN0 neck

Trial Locations (8)

33143

RECRUITING

Miami Cancer Institute, Miami

N6A 5W9

RECRUITING

London Regional Cancer Program, London

H2X 0A9

RECRUITING

CHUM, Montreal

Unknown

RECRUITING

Cork University Hospital, Wilton

RECRUITING

St. Luke's Radiation Oncology Network, Rathgar

H91 T861

RECRUITING

University Hospital Galway, Newcastle Road, Galway

D09FT51

RECRUITING

Beaumont St. Luke's Centre, Dublin

G12 OYN

RECRUITING

Beatson West of Scotland Cancer Centre, Glasgow

All Listed Sponsors
lead

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

OTHER

NCT03997643 - Preservation of Swallowing in Respected Oral Cavity Squamous Cell Carcinoma: Examining Radiation Volume Effects (PRESERVE): A Randomized Trial | Biotech Hunter | Biotech Hunter