NCT03996538View on ClinicalTrials.gov

Vaccination Efficacy With Metformin in Older Adults

PHASE1CompletedINTERVENTIONAL
Enrollment

26

Participants

Timeline

Start Date

June 5, 2019

Primary Completion Date

February 4, 2020

Study Completion Date

February 4, 2020

Conditions
AgingAge-Related ImmunodeficiencyVaccine Response Impaired
Interventions
DRUG

Metformin Hydrochloride Extended-Release Tablets

Subjects will ingest 1500mg/day of metformin hydrochloride extended release. Immune responses will be examined prior to treatment, prior to flu vaccination, and after flu vaccination.

BIOLOGICAL

Influenza Vaccine

All subjects will be vaccinated with high-dose influenza vaccine at the appropriate time of the year per current CDC and FDA recommendations

Trial Locations (1)

06030

UConn Health, Farmington

All Listed Sponsors
lead

UConn Health

OTHER

NCT03996538 - Vaccination Efficacy With Metformin in Older Adults | Biotech Hunter | Biotech Hunter