81
Participants
Start Date
October 1, 2025
Primary Completion Date
February 1, 2028
Study Completion Date
August 1, 2028
Ketogenic diet
Ketocal, a nutritionally complete ready-to-drink liquid, is foreseen to ensure adequate amounts of vitamins and minerals will be used. After 24 weeks a Modified Atkins diet will be started.
Isocaloric diet
Patients will follow an isocaloric diet
Ketone ester supplementation
25g of a ketone monoester, ingested 3 times a day for a period of 12 weeks. Ingestion is separated from a meal and interspersed by at least 4 hours to ensure maximal available ketone bodies circulating in the blood.
UZ Leuven, Leuven
Universitaire Ziekenhuizen KU Leuven
OTHER