Strategies for the Management of Atrial Fibrillation in patiEnts Receiving Dialysis

PHASE2CompletedINTERVENTIONAL
Enrollment

151

Participants

Timeline

Start Date

December 10, 2019

Primary Completion Date

December 31, 2022

Study Completion Date

December 31, 2022

Conditions
Atrial FibrillationEnd Stage Renal Failure on Dialysis
Interventions
DRUG

Warfarin

Individuals randomized to this arm will be exposed to dose-adjusted daily warfarin targeting an international normalized ratio (INR) of 2.0-3.0.

DRUG

Apixaban

Individuals randomized to this arm will receive apixaban 5 mg twice daily (a reduced dose of 2.5 mg twice daily will be given to selected participants).

OTHER

No oral anticoagulation

No oral anticoagulation

Trial Locations (28)

2031

Prince of Wales Hospital, Randwick

2065

Royal North Shore Hospital, Saint Leonards

2747

Nepean Hospital, Kingswood

Unknown

St. George Hospital, Sydney

The Ottawa Hospital - Riverside Campus, Ottawa

V3V 0C6

Surrey Memorial Hospital, Surrey

V6Z 1Y6

St. Paul's Hospital, Vancouver

R2V 3M3

Seven Oaks General Hospital, Winnipeg

B3H 1V7

Nova Scotia Health Authority, QEII Health Sciences Centre, Halifax

L4M 6M2

Royal Victoria Regional Health Centre, Barrie

P3E 5J1

Health Sciences North, Greater Sudbury

L8N 4A6

St. Joseph's Healthcare Hamilton, Hamilton

K7L 2V7

Kingston Health Sciences Centre - Kingston General Hospital, Kingston

N6A 5A5

London Health Sciences Centre, London

L6M 0L8

Halton Healthcare - Oakville Trafalgar Memorial Hospital, Oakville

L1G 2B9

Lakeridge Health Oshawa, Oshawa

P7B 6V4

Thunder Bay Regional Health Sciences Centre, Thunder Bay

M4G 3E8

Sunnybrook Health Sciences Centre, Toronto

M5B 1W8

Unity Health Toronto, at its St. Michael's Hospital site, Toronto

M6K3S2

University Health Network - Toronto General Hospital, Toronto

M6R 1B5

St. Joseph's Health Centre Toronto, Toronto

H1T 2M4

Hôpital Maisonneuve-Rosemont, Montreal

H2X 3E4

Centre Hospitalier de l'Université de Montréal, Montreal

H3T 1E2

Jewish General Hospital, Montreal

H4J 1C5

Hôpital du Sacré-Cœur de Montréal, Montreal

H8S 4K4

McGill University Health Centre, Montreal

G1R 2J6

CHU de Québec - Université Laval, Québec

S4P 0W5

Regina General Hospital, Regina

All Listed Sponsors
collaborator

Canadian Institutes of Health Research (CIHR)

OTHER_GOV

collaborator

The George Institute for Global Health (Sydney, Australia)

UNKNOWN

lead

Unity Health Toronto

OTHER

NCT03987711 - Strategies for the Management of Atrial Fibrillation in patiEnts Receiving Dialysis | Biotech Hunter | Biotech Hunter