Resistance Training and Neuroimaging

NACompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

July 17, 2018

Primary Completion Date

May 16, 2020

Study Completion Date

May 16, 2020

Conditions
Cognitive DeclineCerebrovascular Function
Interventions
BEHAVIORAL

Periodized Resistance Training

Mesocycle I (weeks 1-4) will emphasize muscular hypertrophy to develop a muscular and metabolic base for more intense training in later phases. Training bouts will consist of 4-6 resistance exercises with 2-4 sets per exercise and 8-10 repetitions per set. Mesocycles II (weeks 5-8) and III (weeks 9-12) will emphasize strength development. Training bouts will consist of 4-6 resistance exercises with 3-5 sets per exercise, 4-6 repetitions per set, and linear increases in intensity over time. These parameters were chosen to maximize performance on 4-6 repetition maximum (RM) testing post-intervention, according to the principle of specificity - i.e. specific adaptation to imposed demands.The training loads used will be individually progressed in a safe and effective manner, in order to employ a progressive overload/challenge to the neuromuscular system and elicit the greatest training-induced neuromuscular adaptations possible.

Trial Locations (1)

90089

Clinical Exercise Research Center, Los Angeles

All Listed Sponsors
collaborator

Southern California Clinical and Translational Science Institute

UNKNOWN

lead

Todd Schroeder

OTHER

NCT03982550 - Resistance Training and Neuroimaging | Biotech Hunter | Biotech Hunter