Early Detection of Acute Exacerbation in Patients With Idiopathic Lung Fibrosis - a Pilot Study

NACompletedINTERVENTIONAL
Enrollment

47

Participants

Timeline

Start Date

September 7, 2018

Primary Completion Date

December 31, 2020

Study Completion Date

December 31, 2020

Conditions
Acute ExacerbationIdiopathic Pulmonary FibrosisHome Spirometry
Interventions
OTHER

Home spirometry

Patients will receive a tablet and a spirometer for daily home spirometry. Each patient is supposed to do the home spirometry at the same time every morning. The spirometer and the tablet are connected via Bluetooth. Data will be transferred to a webpage, which team members have access to. Alerts will be automatically send to team members, if the FVC-value decreases about 5% or more within three consecutive days or if the patient does not do the measurement on three consecutive days. Study period is one year. Patients will also conduct a survey to measure health related quality of life (K-BILD). This questionnaire, as well as a phone interview to record changes in medication and condition will be conducted at baseline and every 4 weeks. At baseline and after 3, 6, 9, and 12 months, patients will conduct a 6 minutes walking test, lung function test, blood will be drawn for biomarker analysis, and sputum, nasal swab, and urine samples will be collected and analyzed.

Trial Locations (4)

Unknown

University of Gießen-Marburg, Giessen

LungenClinic Grosshansdorf, Großhansdorf

Medical University Hannover, Hanover

CPC Comprehensive Pneumology Center, München

All Listed Sponsors
collaborator

University of Giessen

OTHER

collaborator

Hannover Medical School

OTHER

collaborator

Ludwig-Maximilians - University of Munich

OTHER

collaborator

LungenClinic Grosshansdorf

OTHER

lead

Heidelberg University

OTHER

NCT03979430 - Early Detection of Acute Exacerbation in Patients With Idiopathic Lung Fibrosis - a Pilot Study | Biotech Hunter | Biotech Hunter