CT Air-trapping for the Early Identification of Benralizumab Responders Among Eosinophilic Asthma Patients

NACompletedINTERVENTIONAL
Enrollment

59

Participants

Timeline

Start Date

June 20, 2019

Primary Completion Date

June 9, 2023

Study Completion Date

June 9, 2023

Conditions
Asthma
Interventions
DRUG

48 weeks of Benralizumab

Benralizumab is administered for 48 weeks (week 0 to week 48) every 4 weeks for the first 3 injections (30 mg sc per injection), and then every 8 weeks for the following 5 injections.

OTHER

Computed tomography

Computed tomography of the thorax is performed at the beginning (week 0), middle (week 24) and towards the end (week 48) of Benralizumab therapy. A sinus scan is also added on weeks 0 and 48.

Trial Locations (2)

13915

Assistance Publique - Hopitaux de Marseille, Marseille

34295

University Hospitals of Montpellier, Montpellier

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

AstraZeneca

INDUSTRY

lead

University Hospital, Montpellier

OTHER