The Role of Cerebellum in Speech

NAActive, not recruitingINTERVENTIONAL
Enrollment

660

Participants

Timeline

Start Date

September 15, 2019

Primary Completion Date

May 31, 2025

Study Completion Date

May 31, 2025

Conditions
Cerebellar AtaxiaDysarthriaHealthy
Interventions
DIAGNOSTIC_TEST

MRI

Brain MRI will be performed (no contrast) to correlate brain anatomy/function with behavioral testing.

DEVICE

TMS

Repetitive TMS will be applied to transiently disrupt cerebellar speech pathways.

BEHAVIORAL

Speech-motor behavioral testing

Language/speaking tasks will be performed during which participants are asked to speak in response to audio/video cues; participants' responses will be recorded. For patients with cerebellar ataxia, additional diagnostic surveys may be completed.

Trial Locations (3)

53705

University of Wisconsin--Madison, Madison

94143

University of California, San Francisco, San Francisco

94720

University of California, Berkeley, Berkeley

All Listed Sponsors
collaborator

University of California, Berkeley

OTHER

collaborator

National Institute on Deafness and Other Communication Disorders (NIDCD)

NIH

collaborator

University of Wisconsin, Madison

OTHER

lead

University of California, San Francisco

OTHER

NCT03972202 - The Role of Cerebellum in Speech | Biotech Hunter | Biotech Hunter