30
Participants
Start Date
May 1, 2019
Primary Completion Date
February 1, 2020
Study Completion Date
May 1, 2020
tranexamic acid
Oral tranexamic acid group(menstrual period\>2days) 250mg bid（exclude menstrual period ）
1064-nm Q-Switched fractional laser
Device: 1064-nm Q-Switched fractional laser is used for melisma with the MASI ≥24 left side of cheek is selected to be treated with 1064-nm Q-Switched fractional laser therapy (8ms, 1.5±0.5J/cm2) once 4 weeks for a total of 5 times
1064-nm Q-Switched laser
Device: 1064-nm Q-Switched laser is used for melisma with the MASI ≥24 right side of cheek is selected to be treated with 1064-nm Q-Switched laser therapy (8ms, 1.5±0.5J/cm2) once 4 weeks for a total of 5 times
Dermatology Derpartment of Xijing Hospital, Xi'an
Air Force General Hospital of the PLA
OTHER_GOV
First Hospital of China Medical University
OTHER
Chinese Academy of Medical Sciences
OTHER
xjpfW
OTHER