13
Participants
Start Date
June 13, 2019
Primary Completion Date
October 13, 2020
Study Completion Date
January 19, 2021
Cyclophosphamide
300 mg/m\^2 intravenous (IV) over 30 minutes on days -5, -4, and -3
Fludarabine
30 mg/m\^2 intravenous (IV) over 30 minutes immediately following the cyclophosphamide on day -5, -4, and -3
Rimiducid
0.4 mg/kg of Rimiducid intravenous (IV) over 2 hours. (A maximum of 2 doses separated by at least 48 hours) Note: Rimiducid may be administered as needed based on the patient condition at the discretion of the Principal Investigator.
Anti-Signaling lymphocytic activation molecule F7 (SLAMF7) chimeric antigen receptor (CAR) T cells
0.3x10\^6- 12.0x10\^6 CAR+ T cells per kg of recipient bodyweight one-time dose on day 0
National Institutes of Health Clinical Center, Bethesda
National Cancer Institute (NCI)
NIH