Symptom-related Screening for Early Detection of CTEPH.

NACompletedINTERVENTIONAL
Enrollment

646

Participants

Timeline

Start Date

January 16, 2019

Primary Completion Date

December 31, 2021

Study Completion Date

February 15, 2022

Conditions
CTEPHPulmonary EmbolismSymptoms and SignsDyspnea
Interventions
DIAGNOSTIC_TEST

dyspnea grade ≥ II according NYHA-WHO

"Intervention Investigator from each center will recover consecutives PE patients and collect baseline, demographic and comorbidities.~In all patients enrolled in the study a short questionnaire regarding dyspnea symptoms will be performed. All patients that refer dyspnea grade ≥ II according NYHA-WHO (6) modified scale will be cited as outpatient to be evaluated~Imaging studies and right heart catheterization is the procedure agreeing with the standard care according to current ESC/ERS Guidelines.~In all patients, the following tests will be performed:~1. Pulsioximetry.~2. Electrocardiogram.~3. Blood sample with determination of NT-ProBNP.~4. Echocardiography. Only an echocardiography indicative of PH warrants further evaluation~5. V/Q scintigraphy. Possible CTEPH can be assumed when mismatched perfusion defects are detected by VQ scan.~6. Right heart catheterization \& Pulmonary CT Scan are required for confirming the diagnosis"

Trial Locations (16)

41014

Hospital Virgen del Rocio, Seville

Unknown

Hospital Universitario Puerto Real, Puerto Real

Consorcio Hospitalario Provincial de Castellón, Castellon

Hospital de Galdakao, Galdakao

Hospital General Universitario de Albacete, Albacete

Hospital Universitario de Bellvitge, Barcelona

Parc Sanitari Sant Joan de Deu, Barcelona

Hospital Universitario Reina Sofía, Córdoba

Hospital Virgen de la Luz, Cuenca

Hospital General Universitario de Elche, Elche

Hospital Universitari de Girona Dr. Josep Trueta, Girona

Hospital Universitari Arnau de Vilanova, Lleida

Hospital Clínico San Carlos, Madrid

Hospital Universitario 12 de Octubre, Madrid

Hospital Universitario Joan XXIII de Tarragona, Tarragona

Hospital Clínico Universitario Lozano Blesa, Zaragoza

All Listed Sponsors
collaborator

Merck Sharp & Dohme LLC

INDUSTRY

collaborator

Sociedad Española de Neumología y Cirugía Torácica

OTHER

lead

Luis Jara-Palomares, MD

OTHER

NCT03953560 - Symptom-related Screening for Early Detection of CTEPH. | Biotech Hunter | Biotech Hunter