ORIN1001 in Patients with Advanced Solid Tumors and Relapsed Refractory Metastatic Breast Cancer

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

58

Participants

Timeline

Start Date

May 25, 2019

Primary Completion Date

January 30, 2023

Study Completion Date

January 30, 2023

Conditions
Advanced Solid TumorMetastatic Breast Cancer
Interventions
DRUG

Abraxane

In patients with relapsed. metastatic breast cancer, ORIN1001 will be administered in combination with Abraxane administered by intravenous infusion.

DRUG

ORIN1001

ORIN1001 will be administered as a table as a monotherapy in the dose escalation phase in patients with advanced solid tumors or in combination with Abraxane in patients with relapse, refractory breast cancer

Trial Locations (20)

10016

NYU Langone Health, New York

11042

Northwell Health, New Hyde Park

Northwell Heath Cancer Institute, New Hyde Park

14203

Roswell Park Comprehensive Cancer Center (RPCCC) (Roswell Park Cancer Institute (RPCI)), Buffalo

19107

Thomas Jefferson University Hospital, Philadelphia

33136

University of Miami Hospital and Clinics - Sylvester Comprehensive Cancer Center, Miami

37203

Sarah Cannon Research Institute, Nashville

44718

Gabrail Cancer Center, Canton

64111

St Lukes Cancer Institute, Kansas City

67214

Cancer Center of Kansas, Wichita

77030

Baylor College of Medicine Medical Center, Houston

80045

University of Colorado Anschutz Medical Campus, Denver

80124

University of Colorado Lone Tree Medical Center, Lone Tree

80129

Highlands Ranch Hospital, Highlands Ranch

85234

Banner MD Anderson Cancer Center, Gilbert

85719

University of Arizona Cancer Center, Tucson

90024

University of California Los Angeles (UCLA) - Jonsson Comprehensive Cancer Center (JCCC) - Oncology Center - Westwood, Westwood, Los Angeles

91505

UCLA Health Burbank Specialty Care, Burbank

92653

UCLA Health Laguna Hills Cancer Care, Laguna Hills

92868

University of California Irvine Medical Center (UCIMC) - Chao Family Comprehensive Cancer Center, Orange

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Orinove, Inc.

INDUSTRY