Subcostal Transversus Abdominis Plane Versus Epidural Block in Abdominal Surgeries

NACompletedINTERVENTIONAL
Enrollment

84

Participants

Timeline

Start Date

May 10, 2019

Primary Completion Date

November 1, 2019

Study Completion Date

January 1, 2020

Conditions
Upper Abdominal Surgery
Interventions
OTHER

Subcostal Transversus Abdominis Plane catheter

"Prior to surgery, an ultrasound guided unilateral Subcostal Transversus abdominis plane bolus dose (consisting of amixture of 10 ml bupivaccaine 0.5% plus 100 mg magnesium sulphate to be completed by normal saline to a total volume of 20 ml mixture) will be given on the same side of the surgical incision.~At the end of surgery, A Transversus abdominis plane catheter will be inserted unilaterally by surgeon during wound closure. Then postoperatively, Transversus abdominis plane infusion of a solution mixture prepared in multiple 50 cm syringes each syringe contain 20 ml bupivacaine 0.5% plus 100 mg magnesium sulphate to be balanced by normal saline to 50 ml solution mixture ( final concentration of bupivacaine is 0.2%). This solution mixture will be infused through Transversus abdominis plane catheter at a rate of 6 ml/hour for 72 hours postoperatively."

OTHER

Epidural catheter

"Prior to surgery, we will site an epidural catheter in the thoracic T7-T9 region, and inject an epidural bolus dose same as described above (consisting of amixture of 10 ml bupivaccaine 0.5% plus 100 mg magnesium sulphate to be completed by normal saline to a total volume of 20 ml mixture) for intra operative analgesia.~Postoperatively, patients will receive epidural infusion of the solution mixture (same as described above) prepared in multiple 50 cm syringes each syringe contain 20 ml bupivaccaine 0.5% plus 100 mg magnesium sulphate to be balanced by normal saline to 50 ml solution mixture ( final concentration of bupivaccaine is 0.2%). This solution mixture will be infused epidurally at a rate of 6 ml/hour for 72 hours (3 days) postoperatively."

Trial Locations (1)

050

Mansoura University, Al Mansurah

All Listed Sponsors
lead

Mansoura University

OTHER

NCT03949452 - Subcostal Transversus Abdominis Plane Versus Epidural Block in Abdominal Surgeries | Biotech Hunter | Biotech Hunter