7
Participants
Start Date
June 1, 2019
Primary Completion Date
December 1, 2021
Study Completion Date
December 1, 2021
Indirect calorimetry
Resting energy expenditure
Skin Temperature
Temperature: supraclavicular, infraclavicular, abdominal, mid-thigh, non-dominant lower arm, middle finger tip, left lower leg, left dorsal foot, ear thermometer
Dual energy X-ray Absorptiometry (DXA)
Body composition
Blood Sampling
thyroid-stimulating hormone (TSH), free triiodothyronine (fT3), free thyroxine (fT4), HbA1c, Fibroblast growth factor 21 (FGF21)
FDG-PET
Dynamic PET scanning of the neck-region
Capillary glucose
Prior to fluorodeoxyglucose (FDG)-PET in order to avoid hyperglycemia
Biopsy of supraclavicular adipose tissue (optional)
Ultrasound guided biopsy of the supraclavicular adipose tissue
University Hospital Basel, Department of Endocrinology, Basel
ETH Zurich
OTHER
University Hospital, Basel, Switzerland
OTHER