153
Participants
Start Date
July 2, 2019
Primary Completion Date
November 25, 2023
Study Completion Date
November 25, 2023
Transseptal Aortic Approach Catheter Ablation Procedure
The transseptal approach entails obtaining femoral venous access, and, guided by fluoroscopy and intra-cardiac ultrasound, starting with a transseptal needle or radio frequency (RF) device inside the dilator of a long sheath; pulling down until the fossa ovalis in the interatrial septum is engaged on both fluoroscopy and intracardiac echo imaging; once on the left side, the long sheath is advanced over the transseptal needle, the needle and dilator are removed, and the ablation catheter can then be advanced across the mitral valve into the left ventricle.
Retrograde Aortic Approach Catheter Ablation Procedure
The retrograde aortic approach entails obtaining femoral arterial access and leaving a sheath in the femoral artery. Under fluoroscopy, an ablation catheter is then advanced up the ascending aorta where the catheter tip is curved using an internal mechanism controlled on the handle of the catheter to form a large loop (to prevent the tip from traveling down a coronary artery and causing trauma such as a dissection); the curved loop is advanced around the aortic arch and down the ascending aorta. To cross the aortic valve with this loop, the catheter is typically torqued in various directions until it falls through the aortic valve and into the left ventricle.
University of Pennsylvania, Philadelphia
Atrium Health/Wake Forest University, Winston-Salem
Vanderbilt University, Nashville
Cleveland Clinic, Cleveland
University of Chicago, Chicago
Washington University in St. Louis, St Louis
Baylor College of Medicine, Houston
Houston Methodist Research Institute, Houston
Texas Cardiac Arrhythmia Research Foundation, Austin
Kaiser Permanente - Colorado, Aurora
University of Colorado, Denver, Denver
University of Utah, Salt Lake City
Banner - University Medical Center, Phoenix
Cedars Sinai Medical Center, Los Angeles
University of California, Los Angeles, Los Angeles
University of California, San Diego, San Diego
San Francisco Veterans Affairs (SFVA) Health Care, San Francisco
University of California, San Francisco, San Francisco
Stanford University, Palo Alto
Oregon Health and Science University, Portland
Hôpital du Sacré-Cœur de Montréal, Montreal
University of California, San Francisco
OTHER